Posted on 11/5/2025 by Nicole Navratil
- Refine procedures for less stress and better sample quality.
- Reduce the number of animals needed to get the same data.
- Replace single animal time-points with longitudinal studies.
- Enhance data quality and throughput.
- Support 24/7 sampling without 24/7 staffing.
- Reinforce Responsibility to prioritize animal welfare and collect valid, accurate data from as few animals as possible.
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This can help when resources are limited or uncertain, by allowing you to increase the number of studies you can perform and the amount of data you can obtain with lean staffing and reduced budgets.
Culex Automated Blood Sampling Systems collect blood samples at preprogrammed time points while the animals move about freely in their home cage. This eliminates the need for human intervention and manual restraint during collection, which can cause stress responses that impact study data. This also allows for overnight sampling without the need for staff to come in to collect the samples, and without disturbing the circadian rhythm.
The Culex NxT was specifically designed for use with rats, mice and other small animals. The larger version, Culex-L is configured to be used with pigs, dogs, non-human primates, and other large animals.
Combining simultaneous blood collection with other collection methods, such as Telemetry systems, Optogenetics Systems, or ISF collection methods like Open Flow Microperfusion and Microdialysis, allow you to collect as much data as possible from a single, freely moving, animal.
Administer drugs, saline, bile salts, or nutritional support through intravenous, subcutaneous, or intraperitoneal routes, with programmable bolus and continuous delivery options suitable for pharmacokinetic, toxicology, and efficacy studies.
Fluid delivery from up to three different syringes into a single implanted catheter is ideal for Drug-Drug Interaction studies, or fluid replacement.
Automated syringe refills maintain continuous rate infusion, including steady state infusion, without the need for technician intervention. Ideal for compounds sensitive to stress or arousal; compounds impacted by disruptions in the circadian/ultradian rhythms; biologics with rapid clearance that require long-term low-rate infusion; radiolabeled or cytotoxic compounds; as well as infectious disease research with pathogens that require ABSL-2 or higher containment.
The Empis can be easily integrated with the Culex Automated Blood Sampling Systems, or used in combination with other systems or study protocols.
The Raturn is a movement responsive rodent caging system that is designed as an alternative to a liquid swivel or commutator to increase animal welfare and avoid jams, leaks, torque, and resistance.
The Raturn interactively responds to animal movement to keep wires, tubing, fluid lines, and cables from twisting; and to allow the animal to move freely without restraint. It is most often used in combination with the Culex Nxt for blood sampling, or used for Cerebral ISF sampling using Open Flow Microperfusion or Microdialysis (either with or without combined blood sampling). However, it can be combined with other sampling systems as well. It is ideal for any method that requires a swivel and/or commutator.
There will also be opportunities to win fun prizes!
Our Team at the Conference:
Dr. Ritesh Vyas, Senior Global Product Strategist
Matt Siebe, Technical Sales Representative
Nicole Navratil, Marketing Director
Candace Rohde-Johnson and Shelly Carballo will be supporting us virtually as well.
Contact us at invivo@basinc.com to schedule a meeting with our team.
Not attending National AALAS? No problem!
Use the same contact information above to schedule a virtual meeting with our team, and visit www.basi-culex.com/resources/ to access our educational materials.