BASi In Vivo News - October 2011
New at BASi
BASi Expanding Capabilities
BASi is expanding our capabilities to meet demand for drug discovery and development services. We have renovated space at our preclinical toxicology site in Evansville, Ind. and will relocate some research services to West Lafayette, creating several new positions. In addition, we added state-of-art research instrumentation at our bioanalytical labs at three sites. See the full news release.
John Devine Promoted
As we enhance our focus on discovery services, Evansville General Manager John Devine Jr., BS, DABT, has been promoted to Vice President of Non-clinical Services. See the full news release.
ACT – 32nd Annual Meeting
November 6 - 9
Phoenix, AZ
Booth #142
Please stop by our booth to talk to our Tox team about how we can help you with services along the entire drug development continuum. We offer technical expertise and services from Discovery to Clinical Proof of Concept.
Enter to Win
When you stop by the BASi booth, be sure to register for a chance to win a Randy Johnson autographed baseball. Johnson, nicknamed "The Big Unit", pitched for the Arizona Diamondbacks and won the Cy Young 5 times. |
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Symposium XI
BASi is sponsoring “Alternative Approaches for Preclinical Development of Biotherapeutic Products.” The event, chaired by John Devine (BASi) and Laura Andrews (Genzyme) will start at 2:00p.m. on Tuesday, November 8th. Topics addressed in this symposium will include general issues related to differences between species that might contribute to species selection/interpretation, considerations into the development of a homologous protein and development and characterization of animal models as relevant species (including KO animals and models of disease).
Meet us
See a list of BASi Representatives attending and schedule a Face-2-Face.
Society for Neuroscience
Washington, DC
November 12-16
Booth #1717
From complete Microdialysis startup packages to microdialysis probes, to the numerous small, yet important accessories, BASi can help outfit your lab. BASi is dedicated to helping you do the best science with the most cost-effective microdialysis products. Take advantage of these microdialysis promotions. Visit Neuroscience booth #1717 or click here to learn more about BASi microdialysis products.
Recent Poster Presentations
Comparison of Dried Blood Spot vs. Plasma Sampling Utilizing the Culex-L Automated Blood Collection System for Canine Pharmacokinetic Studies
Brad Gien, Vance Copper, R. Tyler DeGraw, Candace Rohde Johnson, S. Calugaru, Lori Payne, A.J. Hoehn
P. Downing, R. Sun and L. David Hopper
Culex-L®ABC has been used successfully to perform automated whole blood sample collection in a dog pharmacokinetic study. See how exposure profiles compare when measured in plasma and manually-spotted DBS.
Refinement of Blood Collection Techniques to Permit Automated and Low-stress Sampling from Canines
Candace Rohde Johnson, Brad Gien, Nicholas Suttles, L. David Hopper
A Pharmacokinetic Evaluation of Acetaminophen in Dog Plasma and Dried Blood Spots Using Automated Blood Collection
L. Payne, V. Cooper, S. Calugaru, L.D. Hopper, P. Downing, A. Hoehn, B. Gien, Tyler DeGraw
It is possible regulatory agencies will require submission of data from dual sampling techniques to ensure the validity of data from DBS. BASi seeks to reduce inter-method variability by simultaneously collecting plasma and DBS from the same animal using the Culex® Automated Blood Collection system and then to compare the toxicokinetic parameters.
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For more information about items in this newsletter, or any other BASi product, call 1-800-845-4246, or contact us.
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