BASi In Vivo Sampling Newsletter
May 2009
Culex User's Forum
Long-time Culex users know that BASi used to maintain a Culex User's Forum. This Forum provided an opportunity for all Culex
users to discuss problems, questions, and solutions related to use of the system. We are pleased to announce that the Forum is
back, and with your help it can be better than ever.

The Forum is open to current users only, and requires a user name and password to enter. If you did not receive your password,
or if you would like to have your lab colleagues added to the Forum, contact us via email to request
access.
This Forum provides a safe and convenient place to share information on best practices, but it will need you and your ideas to
keep it relevant. We look forward to working with you to develop the forum into a helpful tool for your Culex studies.
New Culex Website
In an effort to bring all of the BASi products to one central location, we have incorporated the Culex.net website into the BASi
site (www.BASInc.com ). In the process, the Culex website has received a
facelift. We hope you will find the new Culex website easier than ever to navigate. If you have any suggestions about how to make
it better, we'd love to hear them. Please let us know by sending a note via email.

New Lease-to-Own Program
As we all know, the economy is tough; the capital expenditure cuts are even tougher. The Culex team is excited to offer a
lease-to-own option for all of our Culex equipment. Take advantage of the flexible payment schedule to bring the advantages of
automation into your lab. For more information about the new lease-to-own program, contact us via email.
Automated Bile Sampling from Rats via Culex
Bile is one of the most important routes for excretion of drug and drug metabolites, but traditional collection methods
seriously compromise the health of the animal and the quality of your data. The BASi automated approach to bile collection using
Culex and Empis will help overcome these difficulties. Use our system to:
- Collect bile continuously or at programmed intervals
- Recirculate the animal's own bile between collections
- Automatically infuse replacement bile salts during collections
- Maintain samples at 4°C
- Keep everything contained with easy-to-clean sampling lines
- Extend sample collection from healthy animals (up to several weeks)
- Use the Culex to collect blood simultaneously

COMING EVENTS
Boston Visit
Culex Product Manager Candace Rohde will be visiting the Boston area during the first week of June. To set up appointments, please
contact her via email or by calling 1.765.497.8394.
Europe Visit
Candace will also be visiting clients in Europe around the 3rd week of June. If you would like her to visit your facility, please
contact her by email or phone.
AAPS Poster Presentation
A BASi colleague will present the poster "Measuring Induction of Carbamazepine Metabolism in Pigs Using Automated Blood
Sampling" at the AAPS Biotechnology Conference being held in Seattle, Washington June 21 - 24, 2009. The poster will be
presented on Tuesday, June 23. This poster represents work performed on our new Culex-L, the large animal automated sampling
system. For more information about the Culex-L, visit
www.BASInc.com.
Culex® 1-Day In Vivo Workshops
San Diego, CA
Thursday, June 25, 2009
9:00 am to 4:00 pm
Breakfast and lunch provided
Eligible for AALAS CEUs
Surgery Demonstrations
Mouse Cannulations
Bile Cannulations
Microdialysis Implants
Product Demonstrations
Automated Dosing
Automated Blood Sampling
Blood-Brain Barrier Sampling
Single-station Culex Cart
Large-volume Fraction Collector
Empis Infusion System
Space is limited - sign up early! Contact Candace Rohde, Product Manager, via email.
Boston, MA
Tuesday, July 28, 2009
More details to come soon. For early enrollment, contact us via email.
For More Information
To learn more about any of the products and services mentioned in this newsletter, contact us at 800.845.4246:
Natasha Nikolaidis - ext. 815 or email
Candace Rohde - ext. 394 or email
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