BASi In Vivo News - January 2009
Culex® In Vivo 1-Day Workshops
Monday February 2 or Tuesday February 3
9:00 am to 4:00 pm
Continental breakfast and lunch provided
Surgery Demonstrations
Mouse Cannulations
Bile Cannulations
Microdialysis Implants
Product Demonstrations
Automated Dosing
Automated Blood Sampling
Blood-Brain Barrier Sampling
Single-station Culex Cart
Large-volume Fraction Collector
Empis Infusion System
Earn AALAS CEUs
Venue:
Toronto, ON
Space is limited. Sign up early.
Contact Natasha Nikolaidis:
via email
765.497.5815
Waste Containment Kit Bag Clips
After the first of the year, we are no longer shipping the disposable metal bag hangers with our waste containment kits for
Culex (part number CX-5030). Instead, we will include a bag clip with every Culex station that is shipped. These new hangers clip
onto the side of a Culex station, and have a second clip to attach a waste bag, which will support a full 1 liter waste bag. The
new clips are easier to use, and can be used indefinitely instead of being replaced each time. Please let us know if you still need
to get your clips and how many clips you would like, and we will ship a set out to you, email BASi.
New Sterility Indicator
A recent change has been made on all of our Culex Catheters. We have removed the small glass bead from catheter packaging and
replaced it with a sticker indicator. Surgical Technicians will be happy to hear that they won’t have to spend any more time
chasing beads around with a broom and dustpan. The sticker turns from a dull orange to a bright red after undergoing e-beam
sterilization. Please let us know if you have any further questions about the sterility indicator, and we’ll be happy to answer
them.
Rinse Program Now Available
- For Culex users who wish to rinse and re-use tubing sets
- Draws cleaning fluid of user's choice into tubing set, then flushes with water or saline
- Saves technician time, and allows faster turnaround between studies
For more information, email BASi.
Culex-L for Large Animals
The Culex-L is an automated in vivo sampling system for collecting blood and other biological samples from pigs and large
mammals. The system utilizes the same concept as the popular BASi Culex instrument for rodents permitting computer-controlled
dosing and sampling through an implanted catheter, all without human intervention.
The pig is a valuable model for PK/PD and toxicology studies because of its similarities to humans, but manual dosing and
collecting blood or other samples is difficult. Furthermore the man-handling of the animals causes very significant stress which
has been shown to have pharmacological effects. The Culex-L now eliminates human handling during dosing and sampling which
significantly reduces stress in these animals. Under development is specially-designed instrumentation to simultaneously record
important physiological data such as blood pressure, body temperature, ECG and respiratory and heart rates.
The Culex-L Automated In Vivo Sampling System is made to collect pharmacokinetic and pharmacodynamic data during the course of
drug metabolism experiments like no other instrument in the market. For more information, visit
www.culex.net or email BASi.
Training Services
BASi is pleased to offer training services for any of our in vivo products. Our skilled staff will provide training in the use
and maintenance of our instruments, as well as surgical training to implant probes and catheters. No previous surgical experience
is needed – we offer training for novice as well as experienced surgeons. Whether you need complete training on a new instrument,
or a quick refresher course, each training session is tailored to meet your specific needs.
For more information, call 1-800-845-4246, or email BASi.
For More Information
To learn more about any of the products and services mentioned in this newsletter, contact us at 800.845.4246:
Natasha Nikolaidis Ext. 815 or email
Candace Rohde Ext. 394 or email
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