About BASi

Mission statement

It is the vision and mission of BASi to be the leading provider of professional, technical and scientific resources to the drug discovery industry, in service to our clients and to our shareholders.

History

BASi (Bioanalytical Systems, Inc.) established in 1974 has headquarters in West Lafayette, Indiana. It provides contract research services and niche instrumentation, serving the life sciences industries, primarily in drug research and development. BASi was founded by a Purdue University chemistry professor and a group of his doctoral level students. Utilizing their abilities in electrochemistry they developed a line of products to detect trace chemicals in complex matrices. In the late 80’s, BASi entered the services business utilizing liquid chromatography and mass spectroscopy to provide analytical services to clients in their drug discovery efforts. BASi became a public company in 1997. Through a series of acquisitions in the 1990s and 2000s, BASi entered the EU market with a location in England, the preclinical toxicology market with a site near Evansville, Indiana for animal models and veterinary market.

CRO Services

Bioanalytical Services (including GLP)

• Discovery, non-clinical and clinical bioanalytical support
• Large and small molecule capability
• Biomarker assays
• High capacity, fast turnaround sample analysis (Phase 1 support)
• FIM and Phase I support
• Automated sample analysis
• Cutting edge technology: LDTD source and Dried Blood Spot analysis
• All systems Part 11 compliant
• PK kit manufacturing

Non-clinical/GLP Toxicology Services

• IND enabling studies
• Non-clinical animal studies
• Pathology service
• Rodents, rabbits, dogs, swine, monkeys and others
• All dose routes except inhalation
• In-house dose preparation and analytical support

Discovery Research Services

• Research/Discovery experiments: efficacy, target validation, new compound screening
• PK/TK, optionally utilizing BASi’s proprietary Culex^® system
• Automated simultaneous dosing and sampling from conscious freely-moving animals (rodents, dogs, and monkeys)
• Real time data from stress free animals reduces the number of animals used
• Samples: blood, bile, urine and feces
• Automates in-vivo microdialysis sampling from blood and tissues
• Lead optimization allows real time in-vivo ADME experiments

Pharmaceutical Analysis and Stability Program Management (including GMP and GLP)

• Formulation through post-market sample analysis
• Method development, validation, revalidation, transfer
• Stability support, lot release and comparator testing
• Potency, purity, dissolution, water, physical testing
• Stability storage
• Medical device testing
• In vitro bioequivalence analysis

BASi Safe Harbor Certification

The company complies with the U.S.-EU Safe Harbor Framework as set forth by the U.S. Department of Commerce regarding the collection, use, and retention of personal information from European Union member countries. The company has certified that it adheres to the Safe Harbor Privacy Principles of notice, choice, onward transfer, security, data integrity, access, and enforcement. To learn more about the Safe Harbor program, and to view the company’s certification, please visit http://www.export.gov/safeharbor/.

BASi Facilities